N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide

CAS: 218156-96-8

Ref. 3D-FP98779

Product Information

• Name: N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide
• Synonyms: SRPK Inhibitor, Srpin340
• CAS: 218156-96-8

Description

N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide is a new, potent inhibitor of the hepatitis C virus (HCV). It has synergistic effects with other antiviral agents and is effective against murine melanoma. N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide inhibits the HCV NS3/NS4A proteases and blocks HCV RNA replication by inhibiting the polymerase activity and blocking the synthesis of viral proteins. In vitro assays have shown that this drug has antiviral activity for a variety of viruses, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus. This drug also inhibits myeloid leukemia cells in vitro by dephosphorylating

• Brand: Biosynth

Chemical properties

• Molecular weight: 349.35 g/mol
• Formula: C₁₈H₁₈F₃N₃O
• Purity: Min. 95%
• InChI: InChI=1S/C18H18F3N3O/c19-18(20,21)14-4-5-16(24-10-2-1-3-11-24)15(12-14)23-17(25)13-6-8-22-9-7-13/h4-9,12H,1-3,10-11H2,(H,23,25)
• InChI key: InChIKey=DWFGGOFPIISJIT-UHFFFAOYSA-N
• SMILES: O=C(Nc1cc(C(F)(F)F)ccc1N1CCCCC1)c1ccncc1