Eprotirome

CAS: 355129-15-6

Ref. 3D-FPA12915

Product Information

• Name: Eprotirome
• Synonyms: 3-((3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl)amino)-3-oxopropanoic acid, 3-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)anilino]-3-oxo-propanoic acid, 3-[[3,5-Dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino]-3-oxopropanoic acid, Kb 2115, N-[3,5-Dibromo-4-(4-hydroxy-3-isopropylphenoxy)phenyl]malonamic acid, Propanoic acid, 3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino]-3-oxo-

Description

Eprotirome is a thyroid hormone receptor agonist that is used to treat patients with hepatic steatosis and congestive heart failure. Eprotirome has been shown to increase the rate of metabolism, decrease LDL cholesterol, and reduce the risk of atherosclerotic cardiovascular disease. Eprotirome binds to TRs on the cell surface, which increases intracellular cyclic AMP levels by stimulating adenylyl cyclase. This increases the level of active thyroid hormone in the body and leads to a number of effects including increased energy metabolism, decreased LDL cholesterol, reduced cardiac effects, and increased ldl-c lowering.

• Brand: Biosynth

Chemical properties

• Molecular weight: 487.14 g/mol
• Formula: C₁₈H₁₇Br₂NO₅
• Purity: Min. 95%