Quinuclidine
CAS: 100-76-5
Ref. 3D-FQ03738
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 200mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
- 1,4-Ethanopiperidine
- 1,4-Ethylenepiperidine
- Abco
- Chinuclidin
- Nsc 168431
- Quinuclidina
Quinuclidine is a trifluoroacetic acid derivative that has potent antagonistic effects on the nicotinic acetylcholine receptor. It blocks the binding of acetylcholine to its receptor and competes with acetylcholine for binding sites, thereby inhibiting cholinergic neurotransmission. Quinuclidine has been shown to have synergistic effects when combined with other drugs such as neostigmine or atropine, which are used in the treatment of myasthenia gravis. The biological properties of quinuclidine are determined by its detection sensitivity and hydroxyl group. The high values for these properties make it a good candidate for drug development. Quinuclidine is also an effective antagonist of α7 nicotinic acetylcholine receptors, which may be useful in the treatment of Alzheimer's disease.
