Methyl quinoline-6-carboxylate

CAS: 38896-30-9

Ref. 3D-FQ15378

Product Information

• Name: Methyl quinoline-6-carboxylate
• Synonyms: Quinoline-6-carboxylic acid methyl ester, 6-Carbomethoxyquinoline, 6-Quinolinecarboxylic acid, methyl ester, Methyl 6-quinolinecarboxylate

Description

Methyl quinoline-6-carboxylate is a novel opioid receptor antagonist that was synthesized by the authors to study the binding affinity of various derivatives of quinolines. The affinity of these compounds for μ-opioid receptors was established through competitive binding assays, and potent inhibition at this site was found when compared with other known competitive antagonists. Methyl quinoline-6-carboxylate also showed high affinity for the δ receptor and moderate affinity for the κ receptor. This compound was shown to be active in functional assays on cells expressing μ-, δ-, or κ-opioid receptors. In addition, methyl quinoline-6-carboxylate is not psychoactive and has no potential for abuse.

• Brand: Biosynth

Chemical properties

• Molecular weight: 187.19 g/mol
• Formula: C₁₁H₉NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C11H9NO2/c1-14-11(13)9-4-5-10-8(7-9)3-2-6-12-10/h2-7H,1H3
• InChI key: InChIKey=XSRWQTDEIOHXSL-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc2ncccc2c1