Quinacrine dihydrochloride dihydrate

CAS: 6151-30-0

Ref. 3D-FQ35490

Product Information

• Name: Quinacrine dihydrochloride dihydrate
• Synonyms: 1,4-Pentanediamine, N(sup 4)-(6-chloro-2-methoxy-9-acridinyl)-N(sup 1),N(sup 1)-diethyl-, dihydrochloride, dihydrate, 1,4-Pentanediamine, N⁴-(6-chloro-2-methoxy-9-acridinyl)-N¹,N¹-diethyl-, dihydrochloride, dihydrate, 1,4-Pentanediamine, N⁴-(6-chloro-2-methoxy-9-acridinyl)-N¹,N¹-diethyl-, hydrochloride, hydrate (1:2:2), 3-Chloro-7-methoxy-9-[[1-methyl-4-(diethylamino)butyl]amino]acridine dihydrochloride dihydrate, 6-Chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine dihydrochloride dihydrate, Acridine, 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy-, dihydrochloride, dihydrate, Atabrine hydrochloride, Atabrine hydrochloride dihydrate, Ccris 8684, Mepacrine Hydrochloride, Mepacrine hydrochloride dihydrate, N~4~-(6-chloro-2-methoxyacridin-9-yl)-N~1~,N~1~-diethylpentane-1,4-diamine dihydrochloride, N~4~-(6-chloro-2-methoxyacridin-9-yl)-N~1~,N~1~-diethylpentane-1,4-diamine dihydrochloride dihydrate, Quinacrine HCl, Quinacrine hydrochloride, Quinacrine hydrochloride dihydrate
• CAS: 6151-30-0

Description

Quinacrine is a drug that is used to treat diseases caused by protozoa and helminths. It is also used as an adjunct in the treatment of schistosomiasis. Quinacrine binds to DNA and inhibits transcription and replication, which leads to cell death. This drug has been shown to be effective against antibiotic-resistant strains of bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Quinacrine has also been shown to have anti-inflammatory properties. The mechanism of action for this drug may be due to its ability to inhibit Jak2 V617F, a protein that regulates the inflammatory response.

• Brand: Biosynth

Chemical properties

• Molecular weight: 508.91 g/mol
• Formula: C₂₃H₃₀ClN₃O·2HCl·2H₂O
• Purity: Min. 95%