Quercetin 3,4'-dimethyl ether

CAS: 33429-83-3

Ref. 3D-FQ42736

Product Information

• Name: Quercetin 3,4'-dimethyl ether
• Synonyms: 3,4′-Dimethoxy-3′,5,7-trihydroxyflavone, 3,4′-Dimethylquercetin, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-, 5,7,3′-Trihydroxy-3,4′-dimethoxyflavone, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3-methoxy-4H-chromen-4-one, Flavone, 3′,5,7-trihydroxy-3,4′-dimethoxy-, NSC 106970, Quercetin 3,4′-dimethyl ether
• CAS: 33429-83-3

Description

Quercetin 3,4'-dimethyl ether is a flavonoid that is found in many plants and fruits. It has been shown to be effective against leukemia cells, as well as cancer cells from exudates of patients with leukemia. Quercetin 3,4'-dimethyl ether inhibits the activity of histone acetyltransferases, which are enzymes that catalyze the transfer of acetyl groups from acetyl coenzyme A to lysine residues on histones. This inhibition leads to decreased levels of histone H3 acetylation and increased levels of immunosuppression. Quercetin 3,4'-dimethyl ether also has an inhibitory effect on urea nitrogen and nitrogen metabolism pathways by forming hydrogen bonds with reactive groups on proteins such as thioredoxin reductase and glutamine synthetase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 330.29 g/mol
• Formula: C₁₇H₁₄O₇
• Purity: Min. 95%
• InChI: InChI=1S/C17H14O7/c1-22-12-4-3-8(5-10(12)19)16-17(23-2)15(21)14-11(20)6-9(18)7-13(14)24-16/h3-7,18-20H,1-2H3
• InChI key: InChIKey=ZSPZNFOLWQEVQJ-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2OC)cc1O