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Ranirestat
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Ranirestat

CAS: 147254-64-6

Ref. 3D-FR103275

1mgDiscontinued
2mgDiscontinued
5mgDiscontinued
10mgDiscontinued
25mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
Ranirestat
Synonyms:
  • (3R)-2'-(4-bromo-2-fluorobenzyl)-1'H,2H,5H-spiro[pyrrolidine-3,4'-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetrone
  • (3R)-2′-(4-Bromo-2-fluorobenzyl)-1′,2′,3′,4′-tetrahydrospiro[pyrrolidine-3,4′-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5-tetraone
  • (3R)-2′-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4′-1′H-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetraone
  • (3R)-2′-[(4-Bromo-2-fluorophenyl)methyl]spiro[pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetrone
  • As-3201
  • SX-3030(racemate)
  • SX-3202((+)-(S)-isomer)
  • Spiro[pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetrone, 2′-[(4-bromo-2-fluorophenyl)methyl]-, (-)-
  • Spiro[pyrrolidine-3,4′(1′H)-pyrrolo[1,2-a]pyrazine]-1′,2,3′,5(2′H)-tetrone, 2′-[(4-bromo-2-fluorophenyl)methyl]-, (3R)-
  • Sx-3201
  • See more synonyms
Description:

Ranirestat is a fatty acid that is used as a pharmaceutical agent. It is known to be biocompatible and has been shown to have hepatic impairment properties. Ranirestat inhibits DPP-IV, which is an enzyme that degrades the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It has been shown to be effective in treating diabetic patients who are not on any other medications or treatments. Ranirestat has also been shown to prevent or reduce the severity of diabetic neuropathy in animal models. This drug may provide an alternative treatment for diabetes mellitus type 2 by promoting the release of GLP-1 and GIP from intestinal cells, thereby reducing hyperglycemia and improving insulin sensitivity.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
420.19 g/mol
Formula:
C17H11BrFN3O4
Purity:
Min. 95%
InChI:
InChI=1S/C17H11BrFN3O4/c18-10-4-3-9(11(19)6-10)8-21-14(24)12-2-1-5-22(12)17(16(21)26)7-13(23)20-15(17)25/h1-6H,7-8H2,(H,20,23,25)/t17-/m1/s1
InChI key:
InChIKey=QCVNMNYRNIMDKV-QGZVFWFLSA-N
SMILES:
O=C1C[C@@]2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cccn12
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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