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Rimacalib
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Rimacalib

CAS: 215174-50-8

Ref. 3D-FR177034

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Wednesday 8 Jan 2025

Product Information

Name:
Rimacalib
Synonyms:
  • Smp 114
Description:

Rimacalib is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the group of drugs known as COX-2 inhibitors. It inhibits the production of prostaglandins, which are inflammatory and pain-producing compounds. Rimacalib is used in the treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Its clinical use for these diseases is limited by its side effects on the gastrointestinal tract, such as ulcers and bleeding. The most effective dose for Rimacalib is 50 mg twice daily, taken orally with food. This drug binds to the COX-2 receptor in target tissues such as atrial tissue, cardiac tissue, and thp-1 cells. The diameter of these cells was increased following exposure to Rimacalib in cell culture studies. In addition to its anti-inflammatory properties, Rimacalib has been shown to have cardiotoxic effects through cardiac arr

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
394.44 g/mol
Formula:
C22H23FN4O2
Purity:
Min. 95%
InChI:
InChI=1S/C22H23FN4O2/c1-15(17-7-8-18(19(23)13-17)16-5-3-2-4-6-16)20-14-21(29-26-20)25-22(24)27-9-11-28-12-10-27/h2-8,13-15H,9-12H2,1H3,(H2,24,25)/t15-/m0/s1
InChI key:
InChIKey=MYTIJGWONQOOLC-HNNXBMFYSA-N
SMILES:
C[C@@H](c1ccc(-c2ccccc2)c(F)c1)c1cc(/N=C(\N)N2CCOCC2)on1
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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