rac 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

CAS: 67123-97-1

Ref. 3D-FR27407

Product Information

• Name: rac 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
• Synonyms: rac 3-carboxy-1,2,3,4-tetrahydroisoquinolineDL-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acidDL-3-Carboxy-1,2,3,4-tetrahydroisoq uinoline, 1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, 3-Carboxy-1,2,3,4-tetrahydroisoquinoline, 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, <span class="text-smallcaps">DL</span>-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, <span class="text-smallcaps">DL</span>-3-Carboxy-1,2,3,4-tetrahydroisoquinoline, H-Dl-Tic-Oh, H-Tic-Oh, NSC 14794, 3-Isoquinolinecarboxylicacid, 1,2,3,4-tetrahydro-, ()-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, DL-3-Carboxy-1,2,3,4-tetrahydroisoquinoline, 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, DL-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

Description

Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is a potent inhibitor of the Mcl-1 protein. Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid has been shown to inhibit locomotor activity and to have potent inhibitory activity against bacteria. Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid inhibits the antimicrobial peptide LL37 by binding to its active site and prevents LL37 from binding to bacterial cells. Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid also inhibits chloride ion transport in mammalian cells. This compound has low expression in mammalian cells and erythrocytes. It is not toxic to these cells as it does not bind to plasma glucose or proteins in vitro. Rac1

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.2 g/mol
• Formula: C₁₀H₁₁NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C10H11NO2/c12-10(13)9-5-7-3-1-2-4-8(7)6-11-9/h1-4,9,11H,5-6H2,(H,12,13)
• InChI key: InChIKey=BWKMGYQJPOAASG-UHFFFAOYSA-N
• SMILES: O=C(O)C1Cc2ccccc2CN1