Ramipril diketopiperazine

CAS: 108731-95-9

Ref. 3D-FR27677

Product Information

• Name: Ramipril diketopiperazine
• Synonyms: [3S-[2(R*),3a,5a-b,8a-b,9a-b]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid ethyl ester, 2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-, ethyl ester, (αS,3S,5aS,8aS,9aS)-, 2H-Cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic acid, decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl)-, ethyl ester, [3S-[2(R*),3α,5aβ,8aβ,9aβ]]-, [3S-[2(R*),3a,5a,8a,9a]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester, [3S-[2(R*),3a,5ab,8ab,9ab]]-Decahydro-3-methyl-1,4-dioxo-a-(2-phenylethyl)-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazine-2-acetic Acid Ethyl Ester
• CAS: 108731-95-9

Description

Ramipril diketopiperazine is a pharmaceutical preparation that is available in the form of particles. It is a hydrated granulate that contains diacid and sodium carbonate as excipients. This product also contains film-forming polymers, which are used to control the release of drug from the tablet. Ramipril diketopiperazine is used for the treatment of high blood pressure and heart failure. The drug belongs to a class of drugs called angiotensin II receptor antagonists, which prevents the binding of angiotensin II with its receptors, thereby reducing the effects of this hormone on blood pressure, fluid retention, and cardiac function. Ramipril diketopiperazine has been shown to be effective in patients with pravastatin-induced myopathy or cardiomyopathy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 398.5 g/mol
• Formula: C₂₃H₃₀N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C23H30N2O4/c1-3-29-23(28)19(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-18-11-7-10-17(18)14-20(25)22(24)27/h4-6,8-9,15,17-20H,3,7,10-14H2,1-2H3/t15-,17-,18-,19-,20-/m0/s1
• InChI key: InChIKey=KOVMAAYRBJCASY-JBDAPHQKSA-N
• SMILES: CCOC(=O)[C@H](CCc1ccccc1)N1C(=O)[C@@H]2C[C@@H]3CCC[C@@H]3N2C(=O)[C@@H]1C