Rhein

CAS: 478-43-3

Ref. 3D-FR27724

Product Information

• Name: Rhein
• Synonyms: 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid4,5-Dihydroxy-2-anthraquinonecarboxylic acidChrysazin-3-carboxyli c acid, 1,8-Dihydroxy-3-Carboxy anthraquinone, 1,8-Dihydroxy-3-carboxyanthraquinone, 1,8-Dihydroxyanthraquinone-3-carboxylic acid, 2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-, 2-Anthraquinonecarboxylic acid, 4,5-dihydroxy-, 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-, 4,5-Dihydroxy-2-anthraquinonecarboxylic acid, 4,5-Dihydroxy-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylate, 4,5-Dihydroxy-9,10-Dioxo-9,10-Dihydroanthracene-2-Carboxylic Acid, 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, Cassic acid, Chrysazin-3-carboxylic acid, Monorhein, NSC 38629, Rheic acid, Rheinic acid, Rhubarb yellow
• CAS: 478-43-3

Description

Rhein is an analog compound of the alcohol group rhein, which is found in Rhine wine. This compound has cytotoxic activity and inhibits the growth of tumor cells by inhibiting mitochondrial respiration. Rhein also lowers blood sugar levels, which may be due to its lipid solubility and glucose-lowering effect. The surface structures on this molecule are thought to have anti-biofilm properties. The mechanism of action for this drug is unknown, but it has been shown to inhibit marker genes that are involved in tumorigenesis and cell proliferation.

• Brand: Biosynth

Chemical properties

• Molecular weight: 284.22 g/mol
• Formula: C₁₅H₈O₆
• Purity: Min. 98.0 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
• InChI key: InChIKey=FCDLCPWAQCPTKC-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O