Sitafloxacin

CAS: 127254-12-0

Ref. 3D-FS103799

Product Information

• Name: Sitafloxacin
• Synonyms: 3-Quinolinecarboxylic acid, 7-(7-amino-5-azaspiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, [1R-[1α(S*),2α]]-, 3-Quinolinecarboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-, 5-Azaspiro[2.4]heptane, 3-quinolinecarboxylic acid deriv., 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid, 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DU 6859a, Du 6859, Gracevit, Spifloxacin
• CAS: 127254-12-0

Description

Sitafloxacin is a fluoroquinolone antibiotic that has been shown to be effective against gram-positive bacteria. It inhibits bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. Sitafloxacin has been shown to have antibacterial efficacy in experimental models against both Gram-positive and Gram-negative bacteria. Sitafloxacin binds to the gyrase enzyme and inhibits the synthesis of bacterial DNA, leading to cell death by inhibiting protein production. The drug can be used for the treatment of infectious diseases caused by gram-positive bacteria such as Streptococcus pneumoniae, Staphylococcus aureus, or Enterococcus faecalis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 409.81 g/mol
• Formula: C₁₉H₁₈ClF₂N₃O₃
• Purity: Min. 95%
• Color/Form: Solid