Seminalplasmin Fragment (SPF) Analog

CAS: 147958-06-3

Ref. 3D-FS108493

Product Information

• Name: Seminalplasmin Fragment (SPF) Analog
• Synonyms: H-Pro-Lys-Leu-Leu-Lys-Thr-Phe-Leu-Ser-Lys-Trp-Ile-Gly-OH H-PKLLKTFLSKWIG-OH, 13-Lys-seminalplasmin, Seminalplasmin, lysyl(13)-, Spfk-res, Glycine, L-prolyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-threonyl-L-phenylalanyl-L-leucyl-L-seryl-L-lysyl-L-tryptophyl-L-isoleucyl-, L-prolyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-threonyl-L-phenylalanyl-L-leucyl-L-seryl-L-lysyl-L-tryptophyl-L-isoleucylglycine
• CAS: 147958-06-3

Description

Seminalplasmin Fragment (SPF) is a potent antibacterial agent that has been shown to inhibit the growth of Leishmania. It binds to the target cells, forming a covalent bond with the surface of the cell membrane. The SPF analog H-Pro-Lys-Leu-Leu-Lys-Thr-Phe-Leu-Ser-Lys-Trp-Ile-Gly-OH has been shown to have an increased antimicrobial spectrum due to its increased stability in acidic environments. This analog is also active against Gram positive bacteria and can be synthesized using cyclic peptide chemistry. This drug has been shown to have hemolytic activity, meaning that it inhibits red blood cell lysis by binding to phospholipids on the surface of red blood cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,530.89 g/mol
• Formula: C₇₆H₁₂₃N₁₇O₁₆
• Purity: Min. 95%