Sodium bis(thiosulfato)aurate(I)n-hydrate

CAS: 10210-36-3

Ref. 3D-FS151040

Product Information

• Name: Sodium bis(thiosulfato)aurate(I)n-hydrate
• Synonyms: Auricidine, Aurocidin, Aurolin, Auropex, Auropin, Aurosan, Aurothion, Crisalbine, Sodium Aurotosulfate, Gold(1+) Sodium Sulfurothioate (1:3:2), Gold(1+) Sodium Sulfurothioate (1:1:1)

Description

Sodium bis(thiosulfato)aurate(I)n-hydrate is a salt of bis(thiosulfato)aurate(I)-N,O,S. It is an inhibitor of thiol-containing enzymes with clinical relevance for the treatment of rheumatoid arthritis. Sodium bis(thiosulfato)aurate(I)n-hydrate inhibits the enzyme plasma cholinesterase (ChE). It binds to the active site of ChE and prevents it from catalyzing the hydrolysis of acetylcholine in plasma. The inhibitory dose for this drug is not yet known, but it has been shown that a subcutaneous injection at a dosage of 0.5 mg/kg body weight is sufficient to inhibit plasma ChE activity in vivo. The inhibition of ChE leads to an increase in the concentration of acetylcholine in plasma and synovial fluid, which may be responsible for its therapeutic effects on chronic

• Brand: Biosynth

Chemical properties

• Molecular weight: 526.23 g/mol
• Formula: AuH₄Na₃O₈S₄
• Purity: Min. 95%