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Sulforhodamine 101
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Sulforhodamine 101

CAS: 60311-02-6

Ref. 3D-FS41596

5mgDiscontinued
10mgDiscontinued
25mgDiscontinued
50mgDiscontinued
100mgDiscontinued

Discontinued product. For inquiries about similar products, please fill out our form or email us at .


Product Information

Name:
Sulforhodamine 101
Synonyms:
  • 9-(2,4-Disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium inner salt
  • 1H,5H,11H,15H-Xantheno(2,3,4-ij:5,6,7-i'j')diquinolizin-18-ium, 9-(2,4-disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt
  • 1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j′]diquinolizin-18-ium, 9-(2,4-disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-, hydroxide, inner salt
  • 4-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium-9-yl)benzene-1,3-disulfonate
  • 5-(chlorosulfonyl)-2-(2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinolin-4-ium-9-yl)benzenesulfonate
  • Lc 6600
  • Sr 101
  • Sulforhodamine 640
  • Hydrogen 9-(2,4-disulphonatophenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno(2,3,4-ij:5,6,7-i'j')diquinolizin-18-ium
Description:

Sulforhodamine 101 is a fluorescent probe that has been used as a model system to study the effects of apoptotic proteins on cell death. It binds to nuclear DNA and fluoresces when excited with light at 480 nm, which can be detected using a fluorimeter. Sulforhodamine 101 has been shown to have pro-apoptotic properties in cells from human HL-60 leukemia cells and mouse brains. In these experiments, sulforhodamine 101 caused the release of calcium ions from intracellular stores by binding to the ryanodine receptor (RyR1) and inhibiting its function. This led to neuronal death by activating caspases, which are proteases that cleave other proteins. Sulforhodamine 101 also inhibited P-glycoprotein (Pgp) activity in brain tissue samples from rat models, suggesting it may be useful as an inhibitor for this protein in pharmacological agents for brain functions such as memory or learning.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
606.71 g/mol
Formula:
C31H30N2O7S2
Purity:
Min. 95%
Color/Form:
Green Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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