L-Serine beta-naphthylamide

CAS: 888-74-4

Ref. 3D-FS48787

Product Information

• Name: L-Serine beta-naphthylamide
• Synonyms: L-Ser-bNAL-b-Hydroxyalanine b-naphthylamide, H-Ser-.beta.NA, L-Serine Beta-Naphthylamide

Description

L-Serine beta-naphthylamide (LSNA) is a biochemical that is used to treat meningitis caused by Neisseria meningitidis, which is resistant to penicillin. LSNA is an amphipathic molecule and has a carboxyl group on one end and a amide group on the other. It is soluble in water, but dissolves poorly in organic solvents such as chloroform or ether. LSNA inhibits the growth of N. meningitidis by binding to the bacterial cell membrane and causing lysis of the cell wall. This action can be attributed to its amphipathic nature, which allows it to pass through the lipid bilayer of the bacterial membrane. The drug also inhibits proteolytic activity and may inhibit protein synthesis at high concentrations, but this has not been confirmed.

• Brand: Biosynth

Chemical properties

• Molecular weight: 230.26 g/mol
• Formula: C₁₃H₁₄N₂O₂
• Purity: Min. 98%
• Color/Form: Powder
• InChI: InChI=1S/C13H14N2O2/c14-12(8-16)13(17)15-11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12,16H,8,14H2,(H,15,17)/t12-/m0/s1
• InChI key: InChIKey=JOPLDMLMXHNTAX-LBPRGKRZSA-N
• SMILES: N[C@@H](CO)C(=O)Nc1ccc2ccccc2c1