Syrosingopine

CAS: 84-36-6

Ref. 3D-FS65931

Product Information

• Name: Syrosingopine
• Synonyms: (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(éthoxycarbonyl)oxy]-3,5-diméthoxybenzoyl}oxy)-2,11-diméthoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodécahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoléine-1-carboxylate de méthyle, (3Bêta,16Bêta,17Alpha,18Bêta,20Alpha)-18-({4-[(Éthoxycarbonyl)Oxy]-3,5-Diméthoxybenzoyl}Oxy)-11,17-Diméthoxyyohimban-16-Carboxylate De Méthyle, (3b,16b,17a,18b,20a)-18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic Acid Methyl Ester, 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester), Carbethoxysyringoyl Methyl Reserpate, Carbethoxysyringoyl methylreserpate, Hf 41T, Isotense, Londomin, Methyl (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate, Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-({[4-{[(Ethyloxy)Carbonyl]Oxy}-3,5-Bis(Methyloxy)Phenyl]Carbonyl}Oxy)-11,17-Bis(Methyloxy)Yohimban-16-Carboxylate, Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-[({4-[(Ethoxycarbonyl)Oxy]-3,5-Dimethoxyphenyl}Carbonyl)Oxy]-11,17-Dimethoxyyohimban-16-Carboxylate, Methyl (3beta,16beta,17alpha,18beta,20alpha)-18-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-11,17-dimethoxyyohimban-16-carboxylate, Methyl carbethoxysyringoyl reserpate, Methyl reserpate ester of syringic acid ethyl carbonate, Methyl-(1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isochinolin-1-carboxylat, NSC 77030, Raunova, Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate, Seniramin, Singoserp, Siringina, Sml 1908, Su 3118, Syringic acid ethyl carbonate ester with methyl reserpate, Syringopine, Syrosingopin, Yohimban-16-carboxylic acid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-, methyl ester, (3β,16β,17α,18β,20α)-
• CAS: 84-36-6

Description

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 666.71 g/mol
• Formula: C₃₅H₄₂N₂O₁₁
• Purity: Min. 90 Area-%
• Color/Form: White Powder