H-Ser(Bzl)-OH

CAS: 4726-96-9

Ref. 3D-FS72111

Product Information

• Name: H-Ser(Bzl)-OH
• Synonyms: (2S)-2-Amino-3-(benzyloxy)propanoic acid, (2S)-2-Azaniumyl-3-phenylmethoxypropanoate, (S)-2-Amino-3-(benzyloxy)propanoic acid, (S)-2-Amino-3-benzyloxypropionic acid, 3-(Benzyloxy)-<span class="text-smallcaps">L</span>-alanine, <span class="text-smallcaps">L</span>-O-Benzylserine, <span class="text-smallcaps">L</span>-Serine, O-(phenylmethyl)-, Alanine, 3-(benzyloxy)-, <span class="text-smallcaps">L</span>-, H-Ser(Bzl)-OH・HCl, L-Serine, O-(phenylmethyl)-, O-(Phenylmethyl)-<span class="text-smallcaps">L</span>-serine, O-Benzyl-<span class="text-smallcaps">L</span>-serine, O-Benzylserine

Description

H-Ser(Bzl)-OH is a cell cycle inhibitor that has been shown to inhibit the proliferation of breast cancer cells. H-Ser(Bzl)-OH is a serine hydroxamate and is structurally similar to the natural substrate, serine, which it inhibits. It binds to the active site of protein kinase C (PKC), which then cannot phosphorylate other proteins. This inhibition of PKC leads to impaired cell cycle progression, arrest in G2/M phase, and apoptosis. H-Ser(Bzl)-OH also has antibacterial activity against human bacterial pathogens, including methicillin-resistant Staphylococcus aureus and Mycobacterium tuberculosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.22 g/mol
• Formula: C₁₀H₁₃NO₃
• Purity: Min. 95%