[3-(Trifluoromethyl)phenyl]methanol

CAS: 349-75-7

Ref. 3D-FT104980

Product Information

• Name: [3-(Trifluoromethyl)phenyl]methanol
• Synonyms: (3-Trifluoromethylphenyl)methanol, -Benzenemethanol, 3-(trifluoromethyl)-, 1-[3-(Trifluoromethyl)Phenyl]Methanol, 3-(Trifluoromethyl)Benzylic Alcohol, 3-(Trifluoromethyl)benzenemethanol, 3-Hydroxymethylbenzyltrifluoride, 3-Trifluorobenzyl alcohol, 3-Trifluoromethylbenzyl alcohol, Benzyl alcohol, m-(trifluoromethyl)-, M-(Trifluoromethyl)Benzyl Alcohol, M-Trifluoromethylbenzyl Alcohol, Mtf-Byl, Rarechem Al Bd 0072, [3-(Trifluoromethyl)Phenyl]Methanol

Description

3-(Trifluoromethyl)phenylmethanol is an inhibitor of fungal biosynthesis. It binds to the active site of a fungal enzyme called phenol oxidase. This binding prevents the formation of a covalent bond between two molecules, which is necessary for the production of melanin, and thus inhibits the growth of fungi. 3-(Trifluoromethyl)phenylmethanol has been shown to inhibit pyricularia in cell culture at concentrations that are less than 1 nanomolar. A x-ray structure has been determined for this inhibitor bound to its target enzyme. This structural information can be used to design new inhibitors with improved potency and selectivity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 176.14 g/mol
• Formula: C₈H₇F₃O
• Purity: Min. 95%
• InChI: InChI=1S/C8H7F3O/c9-8(10,11)7-3-1-2-6(4-7)5-12/h1-4,12H,5H2
• InChI key: InChIKey=BXEHKCUWIODEDE-UHFFFAOYSA-N
• SMILES: OCc1cccc(C(F)(F)F)c1