3,3-Tetramethyleneglutaric acid

CAS: 16713-66-9

Ref. 3D-FT10893

Product Information

• Name: 3,3-Tetramethyleneglutaric acid
• Synonyms: 1,1-Bis(carboxymethyl)cyclopentane, 1,1-Cyclopentanediacetic Acid, 2,2'-Cyclopentane-1,1-Diyldiacetate, 2,2'-Cyclopentane-1,1-Diyldiacetic Acid, 2-[1-(Carboxymethyl)cyclopentyl]acetic acid, 3,3′-Tetramethylene glutaric acid, Ay 20037, Cyclopentane-1,1-diacetic acid, NSC 39838, Tetramethyleneglutaric acid

Description

3,3-Tetramethyleneglutaric acid (TMG) is a natural compound that is found in oroxylum indicum. It has been shown to have potent inhibitory activity on receptors for the neurotransmitter glutamate, which are involved in the central nervous system and mediate pain. In addition it has been shown to reduce symptoms of diabetic neuropathy. The mechanism of action of TMG is not well understood, but its effects are thought to be mediated by activation of peroxisome proliferator-activated receptor alpha (PPARα), which promotes mitochondrial biogenesis and reduces oxidative stress. TMG has also been shown to be a substrate for reductase enzymes and is believed to induce these enzymes at physiological levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 186.21 g/mol
• Formula: C₉H₁₄O₄
• Purity: Min. 95%
• InChI: InChI=1S/C9H14O4/c10-7(11)5-9(6-8(12)13)3-1-2-4-9/h1-6H2,(H,10,11)(H,12,13)
• InChI key: InChIKey=FWPVKDFOUXHOKQ-UHFFFAOYSA-N
• SMILES: O=C(O)CC1(CC(=O)O)CCCC1