Trypanothione N1,N8-Bis(glutathionyl)-spermidine disulfide
CAS: 96304-42-6
Ref. 3D-FT110135
| 1mg | 645.00 € | ||
| 2mg | 791.00 € | ||
| 5mg | 966.00 € | ||
| 10mg | 1,570.00 € | ||
| 25mg | 2,727.00 € |
Product Information
- Glycinamide, L-γ-glutamyl-L-cysteinyl-N-[3-[[4-[[N-(N-L-γ-glutamyl-L-cysteinyl)glycyl]amino]butyl]amino]propyl]-, cyclic (2→3)-disulfide
- Glycinamide, L-γ-glutamyl-L-cysteinyl-N-[3-[[4-[(L-γ-glutamyl-L-cysteinylglycyl)amino]butyl]amino]propyl]-, cyclic (2→2′)-disulfide
- 1,2-Dithia-6,9,13,18,21-pentaazacyclotetracosane, cyclic peptide deriv.
- Trypanothione
- Trypanothione disulfide
Trypanothione N1,N8-Bis(glutathionyl)-spermidine disulfide is a reactive oxygen species (ROS) scavenger that is produced by the enzyme glutathione reductase and has been shown to be effective against the protozoan leishmania. The reactivity of this molecule is due to its disulfide bond. This reactive cysteine residue can undergo a redox reaction with ROS, which causes cell lysis and leads to the death of the parasite. Trypanothione N1,N8-Bis(glutathionyl)-spermidine disulfide has been shown to have anti-inflammatory properties in mice, which may be due to its ability to inhibit prostaglandin synthesis. It also has been shown to inhibit the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α).
Chemical properties
Technical inquiry about: 3D-FT110135 Trypanothione N1,N8-Bis(glutathionyl)-spermidine disulfide
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