Product Information
TAS-301 is a fatty acid-based drug that has been shown to be chemically stable in vitro. It has been found to have anti-restenosis and anti-inflammatory properties. TAS-301 inhibits the proliferation of muscle cells through its ability to decrease the intracellular calcium concentration and thus, the activation of protein kinase C. It also has been shown to inhibit the growth factor-β1 and basic fibroblast growth factor (bFGF) in vitro, which may lead to an increase in vascular smooth muscle cell proliferation.