4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

CAS: 181219-01-2

Ref. 3D-FT140589

Product Information

• Name: 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
• Synonyms: 2-(4-Pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 4-Pyridylboronic acid pinacol ester, 4-Pyridineboronic acid pinacol ester, Pyridine-4-boronic acid pinacol ester

Description

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a bifunctional inhibitor of the efflux pump of MDR cells. It has been shown to inhibit the function of efflux pumps in MDA-MB-231 cells. This inhibition is due to 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine binding to the transmembrane domains and blocking the transport of drugs. This inhibition has also been seen in vivo and in vitro when used in combination with other antimicrobial agents such as clofazimine. 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine’s inhibitory effects on efflux pumps have been shown using photoc

• Brand: Biosynth

Chemical properties

• Molecular weight: 205.06 g/mol
• Formula: C₁₁H₁₆BNO₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C11H16BNO2/c1-10(2)11(3,4)15-12(14-10)9-5-7-13-8-6-9/h5-8H,1-4H3
• InChI key: InChIKey=NLTIETZTDSJANS-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2ccncc2)OC1(C)C