Tetramethylrhodamine-5-isothiocyanate

CAS: 80724-19-2

Ref. 3D-FT146888

Product Information

• Name: Tetramethylrhodamine-5-isothiocyanate
• Brand: Biosynth
• Description: Tetramethylrhodamine-5-isothiocyanate (TRITC) is a fluorescent dye that can be used for the detection of cancer cells. This molecule interacts with mitochondrial membrane potential and superparamagnetic iron oxide nanoparticles, which are used to detect cancer cells. TRITC is linked to a carrier protein, such as wheat germ agglutinin or streptavidin, and then incubated with the target tissue. The dye is taken up by cells with high mitochondrial membrane potential, which are typically cancerous. The dye can also be detected using an analytical method called flow cytometry, which detects changes in the fluorescence intensity of the dyed cells.TRITC has been shown to have anti-cancer properties in basic fibroblast growth factor-deficient mice and in human colon carcinoma cells in vitro.

Chemical properties

• Molecular weight: 443.52 g/mol
• Formula: C₂₅H₂₁N₃O₃S
• Purity: Min. 95%
• Color/Form: Powder