Product Information
- 2-(t-Butylamino)-acetic acid hydrochloride
- 2-(tert-Butylamino)acetic acid hydrochloride
- Glycine, N-(1,1-dimethylethyl)-, hydrochloride
- Glycine, N-(1,1-dimethylethyl)-, hydrochloride (1:1)
- Glycine, N-tert-butyl-, hydrochloride
- N-t-Butyl Glycine Hydrochloride
- N-t-butylglycine hcl
- N-tert-butylglycine hydrochloride
Tbt-butylglycineHydrochloride is an analog of minocycline, which has been optimized for use in the synthesis of tigecycline. The synthetic process was improved by the addition of a tbt-butyl group to the side chain and optimization of the reaction conditions. This compound is more stable than minocycline, with a higher yield and specificity, which makes it suitable for industrial production. Tbt-butylglycineHydrochloride has been shown to be stable under elemental analysis conditions and in reactions with various chloride salts. The compound is also more soluble than minocycline and can be formulated into tablets or capsules.