Product Information
Name:
Tafamidis meglumine
Synonyms:
- Vyndaqel
- Fx 1006A
- D-Glucitol, 1-deoxy-1-(methylamino)-, 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylate (1:1)
Description:
Tafamidis meglumine is a drug that belongs to the class of drugs for treating cardiomyopathy. It is a prodrug of tafamidis which is hydrolyzed in vivo to its active form, tafamidis meglumine. Tafamidis meglumine has long-term efficacy and prevents the progression of heart failure by inhibiting the development of cardiac hypertrophy. This drug also has been shown to be effective against brain natriuretic peptides and other symptoms such as edema, anemia, and renal dysfunction. Tafamidis meglumine inhibits the activity of protein phosphatase 2A (PP2A), which dephosphorylates cardiac troponin I at serine residue 222. This leads to increased levels of troponin I, which induces apoptosis in cardiomyocytes.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
503.33 g/mol
Formula:
C21H24Cl2N2O8
Purity:
Min. 95%
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HS code:
