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Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate
CAS: 847862-26-4
Ref. 3D-FT167890
| 10mg | 69.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 151.00 € | ||
| 100mg | 213.00 € | ||
| 250mg | 340.00 € |
Product Information
Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate (tBAA) is a heterocycle that has been modified to enhance its pharmacokinetic properties. Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate was designed to be metabolically stable and have a high bioavailability and isosteric properties with phosphatidylinositol, which it uses as a substrate in the catalytic cycle. This modification also increased tBAA's stability in vivo, leading to an increase in efficacy. The covalent attachment of the phenyl ring on the tertiary amine nitrogen of tBAA provides additional protection against hepatic metabolism by CYP450 enzymes, making it more potent than other compounds with similar structures that are not covalently attached to the amine group.
Chemical properties
Technical inquiry about: 3D-FT167890 Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate
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