3,3'-Thiodipropionic acid

CAS: 111-17-1

Ref. 3D-FT171612

Product Information

• Name: 3,3'-Thiodipropionic acid
• Synonyms: 3,3'-Sulfanediyldipropanoate, 3,3'-Sulfanediyldipropanoic Acid, 3,3'-Thiodipropionate, 3,3′-Thiobis[propanoic acid\], 3,3′-Thiodipropanoic acid, 3-[(2-Carboxyethyl)sulfanyl]propanoic acid, 4-Thiaheptanedioic acid, Antioxidant 39620, Bis(2-carboxyethyl) sulfide, Diethyl sulfide 2,2′-dicarboxylic acid, NSC 65523, NSC 8166, Propanoic acid, 3,3′-thiobis-, Propionic acid, 3,3′-thiodi-, Tdpa, Thiodihydracrylic acid, Thiodipropionic acid, Tyox A, β,β′-Thiodipropionic acid

Description

3,3'-Thiodipropionic acid is a fatty acid that has been found to have inhibitory effects on the polymerase chain reaction. It can be used in DNA sequencing and other methods of molecular biology. 3,3'-Thiodipropionic acid inhibits the activity of DNA polymerase by forming a covalent bond with the hydroxyl group on the enzyme's 5' end. This prevents the enzyme from elongating a new strand of DNA, inhibiting DNA synthesis. The compound also reacts with disulfide bonds in proteins and has been shown to inhibit some enzymes such as acetyl-CoA carboxylase and phosphoglycerate kinase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.21 g/mol
• Formula: C₆H₁₀O₄S
• Purity: Min. 95%
• InChI: InChI=1S/C6H10O4S/c7-5(8)1-3-11-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)
• InChI key: InChIKey=ODJQKYXPKWQWNK-UHFFFAOYSA-N
• SMILES: O=C(O)CCSCCC(=O)O