Tetraethyl methylenediphosphonate

CAS: 1660-94-2

Ref. 3D-FT176347

Product Information

• Name: Tetraethyl methylenediphosphonate
• Synonyms: 1-[Diethoxyphosphorylmethyl(ethoxy)phosphoryl]oxyethane, Bis(diethylphosphono)methane, Methanediphosphonic acid tetraethyl ester, Methylenebis(diethoxyphosphine oxide), Methylenebis(diethyl phosphonate), Methylenebis(phosphonic acid) tetraethyl ester, Methylenediphosphonic acid tetraethyl ester, NSC 133889, Phosphonic acid, P,P′-methylenebis-, P,P,P′,P′-tetraethyl ester, Phosphonic acid, methylenebis-, tetraethyl ester, Phosphonic acid, methylenedi-, tetraethyl ester, Tetraethyl Methanediylbis(Phosphonate), Tetraethyl methylenebisphosphonate, Tetraethyl methylidenebisphosphonate

Description

Tetraethyl methylenediphosphonate is a diagnostic agent that has been used to diagnose infectious diseases, including tuberculosis and malaria. It also has antimicrobial properties. Tetraethyl methylenediphosphonate binds to the active site of mitochondrial respiratory complexes I and II, inhibiting the synthesis of ATP by these complexes. This leads to cell death due to lack of energy. Tetraethyl methylenediphosphonate has minimal toxicity and drug interactions, making it an excellent candidate for cancer therapy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 288.21 g/mol
• Formula: C₉H₂₂O₆P₂
• Purity: Min. 95%
• InChI: InChI=1S/C9H22O6P2/c1-5-12-16(10,13-6-2)9-17(11,14-7-3)15-8-4/h5-9H2,1-4H3
• InChI key: InChIKey=STJWVOQLJPNAQL-UHFFFAOYSA-N
• SMILES: CCOP(=O)(CP(=O)(OCC)OCC)OCC