L-threo-ritalinic acid

CAS: 129389-68-0

Ref. 3D-FT28258

Product Information

• Name: L-threo-ritalinic acid
• Synonyms: (a-S,2S)-a-Phenyl-2-piperidineacetic acid
• CAS: 129389-68-0

Description

L-threo-ritalinic acid is a metabolite of methylphenidate, which is an amphetamine used to treat the symptoms of ADHD and narcolepsy. L-threo-ritalinic acid does not have any psychostimulant properties but has been shown to increase dopamine levels in the striatum. It is metabolized by deamination, which is catalyzed by enzymes such as monoamine oxidase or aminopeptidases. L-threo-ritalinic acid's pharmacokinetics are determined by the type of route it takes through the body. In humans, it has been shown that intravenous administration results in a higher concentration than oral administration. The profile for L-threo-ritalinic acid includes its plasma concentrations, which can be measured using a high performance liquid chromatography (LCMS) with tandem mass spectrometry (MS/MS) method.

• Brand: Biosynth

Chemical properties

• Molecular weight: 219.28 g/mol
• Formula: C₁₃H₁₇NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H17NO2/c15-13(16)12(10-6-2-1-3-7-10)11-8-4-5-9-14-11/h1-3,6-7,11-12,14H,4-5,8-9H2,(H,15,16)
• InChI key: InChIKey=INGSNVSERUZOAK-UHFFFAOYSA-N
• SMILES: O=C(O)C(c1ccccc1)C1CCCCN1