2-Thiophenecarboxylic acid hydrazide

CAS: 2361-27-5

Ref. 3D-FT31175

Product Information

• Name: 2-Thiophenecarboxylic acid hydrazide
• Synonyms: 2-Sulfanylbenzohydrazide, 2-Thenoylhydrazine, 2-Thienoylhydrazine, 2-Thienyl hydrazide, 2-Thienylcarboxylic acid hydrazide, 2-Thiophenecarbohydrazide, 2-Thiophenecarbohydrazonic acid, 2-Thiophenecarbonyl hydrazide, 2-Thiophenecarboxylic Hydrazide, Akos Bbs-00004097, Labotest-Bb Lt00772322, NSC 653, Thiophene-2-Carbohydrazide, Thiophene-2-Carboxylic Acid, Thiophene-2-Carboxylic Acid Hydrazide, Thiophene-2-carboxylic hydrazide

Description

2-Thiophenecarboxylic acid hydrazide is a potent antifungal agent that inhibits the growth of bacteria by binding to the cell membrane. It has been shown to be an effective inhibitor of Candida albicans, as well as other fungi, including Saccharomyces cerevisiae and Aspergillus niger. 2-Thiophenecarboxylic acid hydrazide binds to the cell membrane by forming stable complexes with nitrogen atoms in the bacterial cell wall. This binding prevents the formation of an antibiotic-inhibitor complex with enzymes required for protein synthesis, resulting in inhibition of protein synthesis and cell division. 2-Thiophenecarboxylic acid hydrazide also inhibits epidermal growth factor (EGF) activity in vitro, which may be due to its ability to form amide bonds with α1-acid glycoprotein.

• Brand: Biosynth

Chemical properties

• Molecular weight: 142.18 g/mol
• Formula: C₅H₆N₂OS
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C5H6N2OS/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8)
• InChI key: InChIKey=SOGBOGBTIKMGFS-UHFFFAOYSA-N
• SMILES: NNC(=O)c1cccs1