1-(Toluene-4-sulfonyl)piperazine
CAS: 27106-51-0
Ref. 3D-FT37224
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 5g | Discontinued | ||
| 10g | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
1-(Toluene-4-sulfonyl)piperazine
Synonyms:
- 1-(4-Methylbenzenesulphonyl)piperazine
- 1-(4-Methylphenyl)sulfonyl-2,3,5,6-tetrahydropyrazine
- 1-(Toluene-4-sulfonyl)-piperazine
- 1-(p-Tolylsulfonyl)piperazine
- 1-(p-Tosyl)piperazine
- 1-Tosylpiperazine
- N-(p-Toluenesulfonyl)piperazine
- N-(p-Tolylsulfonyl)piperazine
- N-Toluenesulfonylpiperazine
- Piperazine, 1-(p-tolylsulfonyl)-
- See more synonyms
- Piperazine, 1-[(4-methylphenyl)sulfonyl]-
Description:
1-(Toluene-4-sulfonyl)piperazine is an efficient method for the synthesis of epidermal growth factor (EGF). It is a potent antitumor agent with a dihedral angle of 44.5°, and it has been used in the treatment of leukemia, lymphoma, and breast cancer. 1-(Toluene-4-sulfonyl)piperazine also has a high affinity for the epidermal growth factor receptor (EGFR), which is important for its ability to inhibit tumor proliferation. This drug binds to the active site of EGFR, which is located in the extracellular domain of the receptor, and inhibits receptor activation by preventing ligand binding.
Notice:
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Brand:
Biosynth
Long term storage:
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Chemical properties
Molecular weight:
240.32 g/mol
Formula:
C11H16N2O2S
Purity:
Min. 95%
Color/Form:
Powder
InChI:
InChI=1S/C11H16N2O2S/c1-10-2-4-11(5-3-10)16(14,15)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChI key:
InChIKey=VHFDYFUMWJSVCA-UHFFFAOYSA-N
SMILES:
Cc1ccc(S(=O)(=O)N2CCNCC2)cc1
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