Thiamphenicol glycinate HCl

CAS: 2611-61-2

Ref. 3D-FT39338

Product Information

• Name: Thiamphenicol glycinate HCl
• Synonyms: (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate hydrochloride (1:1), (2S,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl glycinate hydrochloride, 2-((Dichloroacetyl)amino)-3-hydroxy-3-(4-(methylsulphonyl)phenyl)propyl (R-(R*,R*))aminoacetate monohydrochloride, Glycine, (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl ester, hydrochloride (1:1), Glycine, (2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl ester, monohydrochloride, Glycine, 2-[(dichloroacetyl)amino]-3-hydroxy-3-[4-(methylsulfonyl)phenyl]propyl ester, monohydrochloride, [R-(R*,R*)]-, Glycine, alpha-ester with D-threo-(+)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide, hydrochloride, Glycine, α-ester with 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]acetamide, monohydrochloride, <span class="text-smallcaps">D</span>-threo-(+)-, Glycine, α-ester with <span class="text-smallcaps">D</span>-threo-(+)-2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]acetamide, monohydrochloride, Neomyson G, Neomyson G HCl, Neomyson G hydrochloride, TPG hydrochloride, Thiamphenicol glycinate hydrochloride, Thiophenicol glycinate, Thiophenicol glycinate hydrochloride, Urfamicin hydrochloride

Description

Thiamphenicol glycinate HCl is a white crystalline powder that is soluble in dimethylformamide. It is used as an antibiotic for the treatment of bacterial infections, which include gram-negative bacteria and chlamydia. Thiamphenicol glycinate HCl has been found to have good water solubility and a high degree of stability in human plasma. Pharmacokinetic studies show that the drug has a low rate of absorption, high protein binding, slow excretion, and low permeability across the blood-brain barrier. Thiamphenicol glycinate HCl also exhibits neuron-protective properties when used to treat meningitis caused by an infectious virus (e.g., herpes simplex virus).

• Brand: Biosynth

Chemical properties

• Molecular weight: 449.73 g/mol
• Formula: C₁₄H₁₉Cl₃N₂O₆S
• Purity: Min. 95%