D-alpha-Tocopheryl polyethylene glycol succinate

CAS: 9002-96-4

Ref. 3D-FT40328

Product Information

• Name: D-alpha-Tocopheryl polyethylene glycol succinate
• Synonyms: TocofersolanVitamin E-TPGS, 2-hydroxyethyl 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl butanedioate, <span class="text-smallcaps">D</span>-α-Tocopherol acid polyethylene glycol 1000 succinate, <span class="text-smallcaps">D</span>-α-Tocopherol polyethylene glycol 1000 succinate, <span class="text-smallcaps">D</span>-α-Tocopheryl polyethylene glycol succinate, Eastman Vitamin ETPGS, Ethoxylated vitamin E succinate, Kolliphor TPGS, Mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] succinate, polyoxyethylene ether, Poly(oxy-1,2-ethanediyl), α-[4-[[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxy-, Poly(oxy-1,2-ethanediyl), α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxy-, [2R-[2R*(4R*,8R*)]]-, Polyethylene glycol vitamin E succinate, Speziol TPGS Pharma, Tocophersolan, Tpgs 1000, Tpgs 1500, Tpgs 400-1000, Tpgs-Ve, Ve-Tpgs 1000, Vedrop, VitE-TPGS, Vitamin E-TPGS, d-α-Tocopheryl poly(ethylene glycol) 1000 succinate, d-α-Tocopheryl polyethylene glycol succinate, α-Tocopherol polyethylene glycol succinate, α-Tocopheryl polyethylene glycol succinate
• CAS: 9002-96-4

Description

D-alpha-Tocopheryl polyethylene glycol succinate (TPGS) is a vitamin E derivative that is active in inhibiting chronic myeloid leukemia. TPGS has been shown to be effective against the resistant K562 cells and may be used as a treatment for chronic myeloid leukemia. This drug binds to the enzyme urokinase-type plasminogen activator, which is essential for cancer cell migration and invasion of tumor tissue. It also inhibits tyrosine kinase, which plays an important role in the development of cancer cells by regulating cellular growth and proliferation. TPGS has been shown to have low bioavailability in humans and is not detectable in plasma after oral administration.

• Brand: Biosynth

Chemical properties

• Formula: C₃₃H₅₄O₅•(C₂H₄O)n
• Purity: Min. 25.0%
• Color/Form: White Slightly Brown Solidified Mass