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N,1,4,4-tetramethyl-8-(4-(4-methylpiperazin-1-yl)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]Quinazoline-3-carboxamide
CAS: 802539-81-7
Ref. 3D-FT40655
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued | ||
| 50mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
Name:
N,1,4,4-tetramethyl-8-(4-(4-methylpiperazin-1-yl)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]Quinazoline-3-carboxamide
Description:
Palbociclib is a drug that inhibits the activity of the cyclin-dependent kinase inhibitors (CDKIs) CDK4 and CDK6. It prevents their phosphorylation, which in turn prevents cells from progressing through the cell cycle. Palbociclib has been shown to be effective against a number of cancers including brain cancer, breast cancer, and ovarian cancer. Palbociclib is not active against non-malignant cells or cells that have already progressed through the cell cycle, such as thymoma cells. The LC-MS/MS method can be used to measure palbociclib levels in plasma and serum samples.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
460.57 g/mol
Formula:
C25H32N8O
Purity:
Min. 95%
InChI:
InChI=1S/C25H32N8O/c1-25(2)14-16-15-27-24(29-20(16)22-19(25)21(23(34)26-3)30-32(22)5)28-17-6-8-18(9-7-17)33-12-10-31(4)11-13-33/h6-9,15H,10-14H2,1-5H3,(H,26,34)(H,27,28,29)
InChI key:
InChIKey=RXZMYLDMFYNEIM-UHFFFAOYSA-N
SMILES:
CNC(=O)c1nn(C)c2c1C(C)(C)Cc1cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc1-2
MDL:
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