4-(Trifluoromethyl)-1H-indole

CAS: 128562-95-8

Ref. 3D-FT43535

Product Information

• Name: 4-(Trifluoromethyl)-1H-indole
• Synonyms: 1H-indole, 4-(trifluoromethyl)-, 4-(Trifluoromethyl)indole

Description

4-(Trifluoromethyl)-1H-indole is a synthetic drug that inhibits the growth of cancer cells. It is a potent inhibitor of cellular proliferation with IC50 values in the micromolar range. 4-(Trifluoromethyl)-1H-indole has been shown to be effective against bladder, prostate, and breast cancer cell lines. This agent also inhibits the production of reactive oxygen species (ROS) in tumor cells. The molecule was synthesized by reacting 5-bromo-2-chloropyrimidine with 1,1,1-trichloroethane and then adding trifluoroacetic acid to produce 4-(trifluoromethyl)-1H-indole. This compound has been shown to bind to the active site of dehydrogenase enzymes and inhibit their activity by stereospecific interactions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 185.15 g/mol
• Formula: C₉H₆F₃N
• Purity: Min. 95%
• InChI: InChI=1S/C9H6F3N/c10-9(11,12)7-2-1-3-8-6(7)4-5-13-8/h1-5,13H
• InChI key: InChIKey=YTVBZSLUNRYKID-UHFFFAOYSA-N
• SMILES: FC(F)(F)c1cccc2[nH]ccc12