3,3',5,5'-Tetraiodo-L-thyronine sodium hydrate

CAS: 25416-65-3

Ref. 3D-FT48192

Product Information

• Name: 3,3',5,5'-Tetraiodo-L-thyronine sodium hydrate
• Synonyms: Levothyroxine sodium hydrate, 3,5,3',5'-Tetraiodothyronine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine, <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate, <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt, hydrate (1:1:?), Beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl]Alanine, L-3,5,3',5'-Tetraiodothyronine, L-T4, Levothyroxine, O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosin, O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodotyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine, T4(Hormone), Tetraiodothyronine, L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt, hydrate (1:1:?), L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate

Description

3,3',5,5'-Tetraiodo-L-thyronine sodium hydrate is a synthetic thyroid hormone that is used to treat hypothyroidism and myxedema coma. It is also used as an ingredient in pharmaceuticals. 3,3',5,5'-Tetraiodo-L-thyronine sodium hydrate has been shown to be effective in the treatment of hypothyroidism and myxedema coma. The drug exhibits a high degree of bioequivalence with levothyroxine sodium tablets.
MRP2/ABCG2 transport proteins are expressed at high levels in the liver and gut epithelium and play a role in the absorption of 3,3',5,5'-tetraiodo-L-thyronine sodium hydrate from the small intestine into blood circulation. This drug binds to sorbitol and d-mannitol through hydrogen bonding interactions. These interactions may be responsible for

• Brand: Biosynth

Chemical properties

• Molecular weight: 798.85
• Formula: C₁₅H₁₀I₄NNaO₄•(H₂O)x
• Purity: Min. 97 Area-%
• Color/Form: Powder