Thr-Ala-OH

CAS: 56217-50-6

Ref. 3D-FT48803

Product Information

• Name: Thr-Ala-OH
• Synonyms: L-Threonyl-L-alanine, 476: PN: WO2005081628 SEQID: 1585 claimed protein, 50: PN: WO2020097235 SEQID: 279 claimed protein, 8: PN: WO2014102101 SEQID: 308 claimed protein, 8: PN: WO2014102104 SEQID: 107 claimed protein, <span class="text-smallcaps">L</smallcap>-Alanine, <smallcap>L</span>-threonyl-, <span class="text-smallcaps">L</smallcap>-Alanine, N-<smallcap>L</span>-threonyl-, <span class="text-smallcaps">L</smallcap>-Threonyl-<smallcap>L</span>-alanine, Alanine, N-threonyl-, Alanine, Threonyl-, H-Thr-Ala-OH, Thr-Ala
• CAS: 56217-50-6

Description

Thr-Ala-OH is a glycopeptide antibiotic that inhibits the synthesis of proteins by binding to aminopeptidases and blocking their activity. It has been shown to be effective against bacteria in the blood group A and B, as well as Trichomonas vaginalis, Giardia lamblia, and Trichomonas homologues. Thr-Ala-OH is synthesized from the amino acid L-threonine and the amino acid alanine. The Thr residue can be replaced with other amino acids such as Ser or Ala without altering its activity. Thr-Ala-OH has been sequenced and found to have a similar structure to phosphofructokinase (the enzyme that generates ATP). As a result, it may inhibit ATP production by binding to phosphofructokinase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 190.2 g/mol
• Formula: C₇H₁₄N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C7H14N2O4/c1-3(7(12)13)9-6(11)5(8)4(2)10/h3-5,10H,8H2,1-2H3,(H,9,11)(H,12,13)/t3-,4+,5-/m0/s1
• InChI key: InChIKey=VPZKQTYZIVOJDV-LMVFSUKVSA-N
• SMILES: C[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)O