L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid

CAS: 42438-90-4

Ref. 3D-FT56013

Product Information

• Name: L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid
• Synonyms: L-Tpi-OH(S)-1,2,3,4-Tetrahydronorharmane-3-carboxylic acid, (-)-(3S)-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic acid, (3S)-1H,2H,3H,4H,9H-Pyrido[3,4-b]indole-3-carboxylic acid, (3S)-2,3,4,9-Tetrahydro-1H-b-carboline-3-carboxylic acid, (3S)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid, (S)-(-)-2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid, (S)-1,2,3,4-Tetrahydro-3-carboxy-2-carboline, (S)-2,3,4,9-Tetrahydro-β-carboline-3-carboxylic acid, 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 2,3,4,9-tetrahydro-, (3S)-, 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 2,3,4,9-tetrahydro-, (S)-, <span class="text-smallcaps">L</span>-1,2,3,4-Tetrahydro-3-carboxy-2-carboline, <span class="text-smallcaps">L</span>-3-Carboxy-1,2,3,4-tetrahydro-β-carboline, Lycoperodine-1
• CAS: 42438-90-4

Description

L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid is a potent antitumor agent that has been shown to be clinically relevant in cancer treatment. It binds to calcium and prevents it from binding to proteins. L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid is metabolized by monoamine oxidase B (MAO-B) and catechol O methyltransferase (COMT), which are enzymes in the brain. The drug also blocks the epidermal growth factor receptor pathway and induces apoptosis protein expression. L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid was detected at low concentrations in renal cell cancer tissue by immunohistochemical analysis. The drug can be used as a marker for renal cell cancer diagnosis and detection sensitivity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 216.24 g/mol
• Formula: C₁₂H₁₂N₂O₂
• Purity: Min. 95%