4-thien-3-ylbenzoic acid
CAS: 29886-64-4
Ref. 3D-FT59073
| 50mg | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued |
Product Information
Name:
4-thien-3-ylbenzoic acid
Synonyms:
- 4-(Thien-3-yl)benzoic acid
- 4-(Thiophen-3-Yl)Benzoic Acid
- Benzoic acid, 4-(3-thienyl)-
- Benzoic acid, p-3-thienyl-
- 4-(3-Thienyl)benzoic acid
Description:
4-Thienylbenzoic acid is a reactive compound that binds covalently to the active site of phosphodiesterase type-5 (PDE5) and blocks the hydrolysis of cyclic nucleotides. This leads to an accumulation of cyclic monophosphate, which can lead to alopecia areata. 4-Thienylbenzoic acid has also been shown to induce laser ablation in mice with alopecia areata. The drug has a high affinity for female sex hormone receptors and is transported by drug transporters such as P-glycoprotein. The drug's concentration-time curve is linear and it has a half-life of 2 hours when administered orally at physiological levels. The logistic regression model showed that the body mass index was significantly correlated with 4-thienylbenzoic acid concentrations.
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
204.25 g/mol
Formula:
C11H8SO2
Purity:
Min. 95%
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HS code:
