Buclizine

CAS: 82-95-1

Ref. 3D-FT61369

Product Information

• Name: Buclizine
• Synonyms: 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine, 1-(4-Tert-Butylbenzyl)-4-(4-Chlorobenzhydryl)Piperazine, 1-(p-Chloro-α-phenylbenzyl)-4-(p-tert-butylbenzyl)piperazine, 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-diethylenediamine, 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)-piperazine, 1-(p-tert-Butylbenzyl)-4-(p-chloro-α-phenylbenzyl)piperazine, 1-[(4-Chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]piperazine, Ah 2526, Aphilan R base, Buclifen, Buclizin, Buclizina, Histabuticine, Histabutizine, Histabutyzine, Hitabutyzyne, Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-α-phenylbenzyl)-, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, Posdel, Postafen

Description

Buclizine is a tricyclic antidepressant drug that is used in the treatment of chronic exposure to various environmental and occupational agents. It has been shown to have a hypoglycemic effect, which may be due to its inhibitory effect on the phospholipid membranes of pancreatic beta cells. Buclizine also inhibits cancer cell growth by inhibiting sodium carbonate-induced activation of protein kinase C and modulates apoptosis by binding to human serum albumin.

• Brand: Biosynth

Chemical properties

• Molecular weight: 433.03 g/mol
• Formula: C₂₈H₃₃ClN₂
• Purity: Min. 95%
• InChI: InChI=1S/C28H33ClN2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3
• InChI key: InChIKey=MOYGZHXDRJNJEP-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1ccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)cc1