Product Information
Name:
(24R)-24-Hydroxycalcitriol
Synonyms:
- 1-alpha,24(R),25-Trihydroxyvitamin D3(1-alpha,3-beta,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol
- (1R,3R,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4R)-4,5-Dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol
- (24R)-1a,24,25-Trihydroxyvitamin D3
- (24R)-1α,24,25-Trihydroxyvitamin D<sub>3</sub>
- 1a,24R,25-Trihydroxycholecalciferol
- 1a,24R,25-Trihydroxyvitamin D3
- 1α,24R,25-Trihydroxyvitamin D<sub>3</sub>
- 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol, (1α,3β,5Z,7E,24R)-
- 9,10-Secocholesta-5,7,10(19)-triene-1,3,24,25-tetrol,(1a,3b,5Z,7E,24R)- (9CI)
- Pri 2193
- See more synonyms
- Ro 21-7729
- 1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4R)-4,5-dihydroxy-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3R,5Z)-
Description:
(24R)-24-Hydroxycalcitriol is a metabolite of vitamin D3. It is a form of vitamin D that is not biologically active and can be converted to calcitriol, the active form of the vitamin, by 24-hydroxylase. This process occurs in the liver and kidneys. (24R)-24-Hydroxycalcitriol has been shown to have minimal activity in animals, but has been shown to inhibit leukemic cells when it is given orally or expressed recombinantly in cultured cells. The effectiveness of this drug may be due to its ability to bind with toll-like receptor 2 on the surface of leukemia cells and activate them, which leads to cellular apoptosis.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
432.64 g/mol
Formula:
C27H44O4
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
