p-(Trifluoromethyl)benzoic acid
CAS: 455-24-3
Ref. 3D-FT64223
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Product Information
- 4-(Trifluoromethyl)Cyclohexanecarboxylate
- 4-(Trifluoromethyl)benzoic acid
- 4-Carboxybenzotrifluoride
- 4-Trifluoromethylbenzoic acid
- Benzoic acid, 4-(trifluoromethyl)-
- C 71640
- Difluoromethylbenzene
- NSC 88327
- p-Toluic acid, α,α,α-trifluoro-
- p-Trifluoromethylbenzoic acid
- See more synonyms
- α,α,α-Trifluoro-p-toluic acid
p-(Trifluoromethyl)benzoic acid (p-TFBA) is an antimycotic and antimicrobial agent that is a white solid. It is soluble in methanol, ethanol, acetone, and ether. p-TFBA has been shown to inhibit the growth of bacteria at concentrations of 2.5-10 micromolar, but not fungi. It also inhibits the growth of some amine oxidases, including fluvoxamine maleate. The exact mechanism of action for p-TFBA is unknown, but it may be due to its ability to react with amines to form a covalent bond and create a reactive radical species that damages DNA or proteins in cells. The reaction with nitrogen atoms can lead to the formation of nitroso compounds which are known carcinogens.
Chemical properties
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