3-(Trifluoromethyl)Phenylurea

CAS: 13114-87-9

Ref. 3D-FT79155

Product Information

• Name: 3-(Trifluoromethyl)Phenylurea
• Synonyms: (3-Trifluoromethylphenyl)urea, 1-[3-(Trifluoromethyl)Phenyl]Urea, 3-(alpha,alpha,alpha-Trifluoro-m-tolyl)urea, 3-(α,α,α-Trifluoro-m-tolyl)urea, 3-Trifluoromethylphenylurea, Didemethylfluometuron, N-(3-Trifluoromethylphenyl)urea, N-[3-(Trifluoromethyl)phenyl]urea, Nsc 136288, Urea, (3-(trifluoromethyl)phenyl)-, Urea, (alpha,alpha,alpha-trifluoro-m-tolyl)-, Urea, (α,α,α-trifluoro-m-tolyl)-, Urea, N-(3-(trifluoromethyl)phenyl)-, [m-(Trifluoromethyl)phenyl]urea
• CAS: 13114-87-9

Description

3-(Trifluoromethyl)phenylurea is a chemotherapeutic agent that is used to treat leukemia and other cancers. It has been shown to be effective in the regression of tumors in mice, when given at a concentration of 1-2 mg/kg. 3-(Trifluoromethyl)phenylurea inhibits cell growth by binding to DNA and inhibiting RNA synthesis. The optimal concentrations for 3-(trifluoromethyl)phenylurea are determined using an equation that includes coefficients obtained from stepwise regression analysis. The coefficient values are also optimized using topological descriptors and genetic algorithms.

• Brand: Biosynth

Chemical properties

• Molecular weight: 204.15 g/mol
• Formula: C₈H₇F₃N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C8H7F3N2O/c9-8(10,11)5-2-1-3-6(4-5)13-7(12)14/h1-4H,(H3,12,13,14)
• InChI key: InChIKey=FQEIBEOBXKJAMZ-UHFFFAOYSA-N
• SMILES: NC(=O)Nc1cccc(C(F)(F)F)c1