3-(2-Tetrahydrofuryl)-5-fluorouracil

CAS: 63901-83-7

Ref. 3D-FT82872

Product Information

• Name: 3-(2-Tetrahydrofuryl)-5-fluorouracil
• Synonyms: 2,4(1H,3H)-pyrimidinedione, 5-fluoro-3-(tetrahydro-2-furanyl)-, 5-Fluoro-3-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione, 5-Fluoro-3-(tetrahydro-2-furanyl)-2,4-pyrimidinedione

Description

3-(2-Tetrahydrofuryl)-5-fluorouracil (3HFTU) is a fluorinated analog of 5-fluorouracil, a drug used in the clinical treatment of cancer. 3HFTU is used as an adjuvant therapy to increase the uptake and inhibitory properties of 5-fluorouracil in tumor tissue. This compound has been shown to be effective in inhibiting the growth of tumors by reducing their size and spread. 3HFTU has also been shown to have inhibitory properties against DNA synthesis, RNA synthesis, and protein synthesis. The chemical ionization technique is used to measure the diameter of 3HFTU particles. 3HFTU samples are prepared for measurement by adding a solvent that dissolves all solids and then filtering away the solids.
A clinical use for this product is to provide adjuvant therapy for patients with cancerous tumors, who are undergoing radiation therapy or

• Brand: Biosynth

Chemical properties

• Molecular weight: 200.17 g/mol
• Formula: C₈H₉FN₂O₃
• Purity: Min. 95%
• InChI: InChI=1S/C8H9FN2O3/c9-5-4-10-8(13)11(7(5)12)6-2-1-3-14-6/h4,6H,1-3H2,(H,10,13)
• InChI key: InChIKey=MGYWDJWGVICAEL-UHFFFAOYSA-N
• SMILES: O=c1[nH]cc(F)c(=O)n1C1CCCO1