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1-[4-(Trifluoromethyl)Phenyl]-2-Pyrrolidinone
CAS: 73081-88-6
Ref. 3D-FT89090
| 1g | Discontinued | ||
| 2g | Discontinued | ||
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
1-[4-(Trifluoromethyl)Phenyl]-2-Pyrrolidinone
Synonyms:
- 2-Pyrrolidinone, 1-[4-(trifluoromethyl)phenyl]-
Description:
1-[4-(Trifluoromethyl)phenyl]-2-Pyrrolidinone is an antagonist of the 5-HT1D receptor. It is a potent and selective antagonist of the 5-HT1D receptor with a Kd of 2.6 nM at the 5-HT1D receptor, 1,000 times more potent than mianserin. This drug has shown efficacy in animal models of depression and anxiety, as well as in human clinical trials. The 1-[4-(trifluoromethyl)phenyl]-2-pyrrolidinone has been found to be useful for treating various disorders such as depression or other conditions that are responsive to treatment with serotonin agonists or antagonists. The 1-[4-(trifluoromethyl)phenyl]-2-pyrrolidinone has also been found to be useful for treating diseases that are responsive to treatment with an antagonist of the 5-
Notice:
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Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
229.2 g/mol
Formula:
C11H10F3NO
Purity:
Min. 95%
InChI:
InChI=1S/C11H10F3NO/c12-11(13,14)8-3-5-9(6-4-8)15-7-1-2-10(15)16/h3-6H,1-2,7H2
InChI key:
InChIKey=RNCNLNNXQWEWLX-UHFFFAOYSA-N
SMILES:
O=C1CCCN1c1ccc(C(F)(F)F)cc1
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