Uracil-4-acetic acid

CAS: 4628-39-1

Ref. 3D-FU08315

Product Information

• Name: Uracil-4-acetic acid
• Synonyms: 6-Carboxymethyluracil, (2,6-Dihydroxypyrimidin-4-yl)acetic acid, (2,6-Dioxo-1,2,3,6-Tetrahydropyrimidin-4-Yl)Acetate, (2,6-Dioxo-1,2,3,6-Tetrahydropyrimidin-4-Yl)Acetic Acid, 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidineacetic acid, 2-(2,4-Dioxo-1H-pyrimidin-6-yl)acetic acid, 2-(2,6-Dihydroxypyrimidin-4-yl)acetic acid, 2-(2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)acetic acid, 2-(2-Hydroxy-6-oxo-1,6-dihydropyrimidin-4-yl)acetic acid, 2-(6-Hydroxy-2-oxo-2,3-dihydropyrimidin-4-yl)acetic acid, 4-Pyrimidineacetic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, 6-Uracilacetic acid, Ai3-25481, Nsc 13201

Description

Uracil-4-acetic acid is a monocarboxylic acid that is synthesized in mammalian cells. It can also be obtained by hydrolysis of orotic acid, which was previously synthesized from uridine and phosphorolysis of sephadex g-100. Uracil-4-acetic acid is used to produce uridine through the action of an enzyme called uridine phosphorylase. This enzyme catalyzes the reaction between ATP and uracil, as well as the conversion of orotic acid to orotidine 5′-monophosphate decarboxylase. Uracil-4-acetic acid has been shown to inhibit the growth of toxoplasma, but it has not been determined whether this inhibition is due to its role in the synthesis of uridine or its toxic effects on the parasite.

• Brand: Biosynth

Chemical properties

• Molecular weight: 170.12 g/mol
• Formula: C₆H₆N₂O₄
• Purity: Min. 95%
• Color/Form: White Solid
• InChI: InChI=1S/C6H6N2O4/c9-4-1-3(2-5(10)11)7-6(12)8-4/h1H,2H2,(H,10,11)(H2,7,8,9,12)
• InChI key: InChIKey=NQAUNZZEYKWTHM-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1cc(=O)[nH]c(=O)[nH]1