Velneperit

CAS: 342577-38-2

Ref. 3D-FV103247

Product Information

• Name: Velneperit
• Synonyms: Cyclohexanecarboxamide, 4-[[(1,1-dimethylethyl)sulfonyl]amino]-N-[5-(trifluoromethyl)-2-pyridinyl]-, trans-, N-[5-(Trifluoromethyl)-2-pyridinyl]-trans-4-[[(1,1-dimethylethyl)sulfonyl]amino]cyclohexane-1-carboxamide, N-[5-(Trifluoromethyl)pyridin-2-yl]-trans-4-(tert-butylsulfonylamino)cyclohexane-1-carboxamide, S 2367, trans-4-[[(1,1-Dimethylethyl)sulfonyl]amino]-N-[5-(trifluoromethyl)-2-pyridinyl]cyclohexanecarboxamide

Description

Velneperit is a drug used to treat chronic oral diabetes and cardiac disorders. It is an inhibitor of the enzyme DPP-IV, which regulates blood sugar levels by breaking down glucagon-like peptide 1 (GLP-1). Velneperit also has properties that inhibit the binding of epidermal growth factor (EGF) to its receptor. This drug has been shown to be effective in treating congestive heart failure and certain types of metabolic disorders. Velneperit is an analog of exenatide, which was approved for use in 2013. Velneperit binds to the same receptor as exenatide but has a longer half-life than exenatide because it is more stable than exenatide due to its hydrogen bond formation between the hydroxyl group on the alpha carbon atom and the oxygen atom on phenylalanine at position 6.

• Brand: Biosynth

Chemical properties

• Molecular weight: 407.45 g/mol
• Formula: C₁₇H₂₄F₃N₃O₃S
• Purity: Min. 95%