Wilforgine
CAS: 37239-47-7
Ref. 3D-FW42590
| 1mg | Discontinued | ||
| 2mg | Discontinued | ||
| 5mg | Discontinued | ||
| 10mg | Discontinued | ||
| 25mg | Discontinued |
Product Information
- Evonimine, 8-(acetyloxy)-O2-deacetyl-8-deoxo-O2-(3-furanylcarbonyl)-, (8α)-
- 3-Furancarboxylic acid, (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,17,18,19,20-dodecahydro-21-hydroxy-8,18,21-trimethyl-5,17-dioxo-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridin-14-yl ester
- Wilforgin
Wilforgine is a drug that has been approved in China for the treatment of cancer. This drug has a synergic effect with chlorantraniliprole, and it can be used as an adjuvant agent to prevent or treat cancers. The matrix effect is the result of wilforgine's ability to inhibit the synthesis of proteins and nucleic acids. Wilforgine also has a long-term efficacy, which may be due to its ability to inhibit cancer cells from entering into mitosis. Wilforgine is a natural product obtained from Tripterygium wilfordii, a Chinese herb that has been used for centuries in traditional Chinese medicine. It can be extracted from Tripterygium wilfordii by subcritical water extraction, and purified by preparative high-performance liquid chromatography (PHTLC). Pharmacokinetic studies have shown that wilforgine is rapidly absorbed after oral administration, distributed widely in the body, and metabolized by the liver
