2-(4-Bromophenyl)-1H-indole
CAS: 6127-49-7
Ref. 3D-GAA12749
| 1g | To inquire | ||
| 5g | To inquire | ||
| 10g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
- 1H-indole, 2-(4-bromophenyl)-
2-(4-Bromophenyl)-1H-indole is a ligand, which binds to the benzodiazepine receptor in the central nervous system. 2-(4-Bromophenyl)-1H-indole is synthesised and tested for its affinity for this receptor. The uptake of 2-(4-bromophenyl)-1H-indole into rat brain tissue is studied using autoradiography. It is found that 2-(4-bromophenyl)-1H-indole has high affinity for the benzodiazepine binding site on rat brain membranes and modulates the activity of GABA receptors, which causes sedation. The effects of halogens on 2-(4-bromophenyl)-1H-indole are investigated by measuring their effect on its uptake into rat brain tissue. Flumazenil, an antagonist of benzodiazepine receptors, blocks the effects of 2-(4-bromophenyl)-1H
Chemical properties
Technical inquiry about: 3D-GAA12749 2-(4-Bromophenyl)-1H-indole
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